Monday, March 29, 2010

Silymarin supplements don't work?

Steve - a recent piece from the Healthy Skeptic from the New York Times, while lauding the benefits of silymarin injections, questioned the viability oral supplements. For the doctor quoted in the piece who said there is no data supporting its efficacy, he is mistaken.

http://nutritionalconcepts.blogspot.com/2010/03/research-highlights-march.html
http://nutritionalconcepts.blogspot.com/2009/12/milk-thistle-cuts-liver-toxicity-from.html
http://nutritionalconcepts.blogspot.com/2007/11/milk-thistle-may-protect-against-liver.html

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Ferenci P, Dragosics B, Dittrich H, et al. Randomized controlled trial of silymarin treatment in patients with cirrhosis of the liver. J Hepatol 1989;9:105-13.

Velussi M, Cernigoi AM, De Monte A, et al. Long-term (12 months) treatment with an anti-oxidant drug (silymarin) is effective on hyperinsulinemia, exogenous insulin need and malondialdehyde levels in cirrhotic diabetic patients. J Hepatol 1997;26:871-9.

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Buzzelli G, Moscarella S, Giusti A, et al. A pilot study on the liver protective effect of silybin-phosphatidylcholine complex (IdB1016) in chronic active hepatitis. Int J Clin Pharmacol Ther Toxicol 1993;31:456-60.

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1 comment:

Johno said...

Milk thistle and other supplements like
Liv 52 help liver function
along with a large intake of water.