Long-term lifestyle intervention (diet, exercise, or both) helps women with impaired glucose tolerance live longer, according to the results of a study presented at the American Diabetes Association 72nd Scientific Sessions. The findings come from 23 years of follow-up data on participants in the Da Qing Diabetes Prevention Study.
In 1986, subjects with a mean age of 45 years, from 33 clinics, with impaired glucose tolerance were randomly assigned to a control group or to 1 of 3 lifestyle intervention groups (diet, exercise, and diet plus exercise). The intervention took place from 1986 to 1992. In 2009, 23 years after randomization, the long-term effects of the intervention on all-cause and cardiovascular (coronary heart disease, stroke, and sudden death) mortality were determined.
In women, lifestyle intervention reduced all-cause mortality by 53% in the intervention group compared with 29.3% in the control group. The reduction in all-cause mortality in women was mainly due to differences in cardiovascular mortality (heart disease and stroke).