Increased intakes of vitamin E may reduce the risk of bladder cancer by about 35 per cent, says a new study from an international team of researchers published in Cancer Causes and Control. The study also showed that carotenoids, niacin, thiamine, and vitamin D may reduce the risk of bladder cancer in older people. “Future studies should focus on optimal doses and combinations of these micronutrients particularly for high risk groups such as heavy smokers and older individuals,” researchers state.
Dietary data from 322 people with bladder cancer and 239 healthy controls showed that, in general, people with the highest average intakes of vitamin E (at least 193.4 milligrams per day) were 34 per cent less likely to develop bladder cancer. When the researchers focused their analysis on smokers, they found that the highest intakes of vitamin E, carotenoids (18 milligrams), and niacin (46.5 milligrams), were associated with a 42, 38, and 34 per cent reduction in bladder cancer risk in heavy smokers. In older individuals, the highest average intakes of carotenoids, vitamin D (641 International Units), thiamin (3.35 milligrams), niacin, and vitamin E were all associated with a reduced bladder cancer risk.
The study was supported by the National Institute of Environmental Health Sciences and the National Cancer Institute at the US National Institutes of Health (NIH).