Sunday, January 03, 2010

No Benefit of Ginkgo Biloba for Age-Related Cognitive Decline

Results of a randomized trial show no effect of ginkgo biloba supplements on the rate of cognitive decline in adults with either normal cognition or mild cognitive impairment. The Ginkgo Evaluation of Memory (GEM) study, a large randomized trial, showed that use of the popular herbal supplement in a dose of 120 mg twice daily was no different than placebo in terms of cognitive outcomes during a median follow-up of 6 years. "There were changes of normal aging in the general testing and in all 4 cognitive domains, but there was no separation between the 2 curves; they were virtually completely superimposable," said senior author Steven T. DeKosky, MD, from the University of Pittsburgh, Pennsylvania. The study is published in the Journal of the American Medical Association.

Steve - this is not a surprise. Many other studies prior to this one has shown the same results. We have not recommended this supplement for cognitive decline for many years.

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