Low vitamin D linked to osteoarthritis

Low levels of vitamin D are associated with the loss of cartilage in the knee joint of older individuals. Researchers found osteoarthritis patients with vitamin D sufficiency have approximately 1.5 percent less loss of knee cartilage per year than patients with vitamin D deficiency.

The investigators measured levels of vitamin D in blood samples and knee cartilage volume on X-rays from 880 men and women who were 51 to 79 years old. The team then took similar measurements again almost 3 years later among 353 of the study participants, the researchers report in the journal Arthritis & Rheumatism.

Overall, 58 percent of these subjects showed changes in knee cartilage indicating worsening osteoarthritis between the first and second measurements, and half reported knee pain.

Both at the beginning of the study enrollment and at follow up, men and women with vitamin D deficiency had lower knee cartilage volume and were more likely to experience knee pain.