Friday, February 27, 2009

Diet drug Xenical (Orlistat) enourages poor eating habits

Orlistat is a lipase inhibitor that reduces the intestinal absorption of fat and may enhance the effects of dietary and behavioral therapy on weight loss and maintenance. The present study examined the effect of orlistat on dietary intake, especially fat intake, during long-term weight maintenance.

The Journal of Human Nutrition and Dietetics study concluded that the use of orlistat compared with placebo in a lifestyle modification program does not appear to influence dietary intake and, in fact, worsened dietary habits. Subjects that chose to take orlistat after the end of the program did not comply with dietary recommendations and this may hamper the effect of the drug.

Steve - this is not surprising to see. For what little effect this drug has, it is completely wasted on those who think they can now eat whatever they want (similar to the statin drug effect).

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