Multis Are a Matter of the Heart

Women who used multivitamin and mineral supplements for longer than three years reduced their risk of dying of cardiovascular disease (CVD) in a new study of U.S. adults (J. Nutr. 2015. Published online Jan. 7, 2015).

The study used data from more than 8, 600 subjects 40 years or older (from the NHANES III, 1988 to 1994) as well as mortality data reported by the National Death Index through 2011. They found a significant association with those who used the supplements for longer than three years compared with nonusers. This finding was largely driven by the significant association among women.

This research follows a number of studies showing multivitamins’ positive effects on heart health. In 2010, the use of multivitamins was inversely associated with heart attacks in women, especially those without a history of CVD who used the supplements for five years or longer (Am J Clin Nutr. 2010 Nov;92(5):1251-6). That study included 31,000 women with no history of CVD and 2,200 women with a history of CVD aged 49 to 83 years from Sweden.

Additionally, a 2003 study from Stockholm reported Low-dose multivitamins may prevent heart attacks in subjects aged 45 to 70, and another study from the same year found multivitamins with antioxidant properties had beneficial effects on homocysteine and low-density lipoprotein (LDL) oxidation measures.