Wednesday, November 07, 2012

Lactobacillus GG's bioavailability confirmed

A double-blind, placebo-controlled study in British Journal of Nutrition was conducted to determine whether consumption of probiotic Lactobacillus rhamnosus GG (GG) would lead to the recovery of GG in a tonsil tissue. After 3 weeks' daily consumption of GG as a single strain (n 20), GG as a part of a multispecies combination (n 17) or placebo (n 20), tonsil tissue samples were collected from young adults during tonsillectomy due to chronic or recurrent tonsillitis. GG was recovered in the tonsil sample of 40 % of the subjects in the GG group, 41 % in the multispecies group and 30 % in the placebo group. In all subjects with positive recovery of GG in the tonsil tissue, GG was also recovered in the fecal sample taken at the start of the intervention and at the time of the tissue sample collection, which indicates more persistent adherence of the probiotic. To conclude, GG can be recovered from tonsil tissue after oral administration as a single-strain probiotic or as a part of a multispecies probiotic combination.

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