CoQ10 support for Parkinson's Disease

Mitochondrial dysfunction has been well established to occur in Parkinson's disease and appears to play a role in the pathogenesis of the disorder. A deficit in brain coenzyme Q10 status may be involved in the pathophysiology of Parkinson's disease. Mitochondria play a central role in apoptotic cell death through a number of mechanisms. Coenzyme Q10 as an antioxidant, can affect certain of these processes. Theoretically, coenzyme Q10 can interfere with Parkinson's disease progression. There are four randomized, double-blind, placebo-controlled trials that tested coenzyme Q10 for Parkinson's disease. The results show coenzyme Q10 at dose of 1200mg/d for 16 months is well-tolerated and might disability as measured improve Parkinson's outcomes. The Cochrane Collaboration 12/7/2011