Wednesday, May 04, 2011
Soy has hormonal effect in kids: Japanese study
In the May, 2011 issue of American Journal of Epidemiology, researchers investigated whether soy intake is associated with sex  steroid levels in Japanese children. This cross-sectional                      study was conducted in autumn 2006. Subjects were  substantially healthy preschoolers, 230 boys and 198 girls, aged 3–6  years.                      Dietary data, including soy intake, were assessed  using 3-day dietary records. Urinary  estrone, estradiol, testosterone, and 5-androstene-3β,17α                      diol levels measured using liquid  chromatography–electrospray ionization tandem mass spectrometry, and  urinary dehydroepiandrosterone                      level measured with a radioimmunoassay, were  adjusted for urinary creatinine levels. In the analysis of covariance  for sex                      steroids after adjustments for age and body mass  index, soy intake was significantly negatively related to estrone and  estradiol                      in boys and positively related to testosterone and  5-androstene-3β,17α diol in girls. Isoflavone had a significant tendency                      to be negatively associated with estradiol in boys  and to be positively associated with testosterone in girls. Total energy                      intake was not associated with any sex steroids in  boys or girls. These results suggest that soy intake might affect the  secretion                      or metabolism of sex steroids in childhood and that  the effects might differ by sex.
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What does this practically mean for kids? What is the long-term effect?
That remains to be seen. The data has been positive and negative. Our philosophy for young children is that with drinks (excluding formula, of course), whether cow's milk, soy milk, rice milk, etc., do not consume the same one every day. Mix it up so that there is balance. This reduces the potential for allergy, intolerance, and excess exposure to substances such as phytoestrogens. But we do not dissuade parent from giving soy products to their children unless there is an allergy/intolerance.
Another aspect that was not considered in this study is that conventional soy products have a much higher estrogen content than organic soy due to the pesticide load. Always choose organic soy!
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