Friday, July 03, 2009

'Hidden' Lactose in Drugs Used for the Treatment of GI Conditions

Lactose is the most common form of excipient used in drug formulations and may be overlooked when advising these patients.

A wide range of medications prescribed for the treatment of gastrointestinal conditions contain lactose. We have quantified the lactose content in a selection of medications using HPLC. Lactose is present in amounts that may contribute towards symptoms. Lactose-free alternatives were also identified.

Lactose is present in a range of medications and may contribute towards symptoms. This may not be recognized by the prescribing doctor as excipients are not listed in the BNF, and the quantity of lactose is not listed on the label or in the accompanying manufacturer's leaflet.

Alimentary Pharmacology & Therapeutics, July 1 2009

Bonnie - finally they recognize this? Now they have to acknowledge cornstarch, artificial food dyes, talc, and more.

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