Thursday, November 10, 2005

B vitamins to lower homocysteine may prevent strokes

Taking high doses of B vitamins may help reduce the risk of a second stroke and heart attacks, according to a new analysis.

The B vitamin group, including folic acid, B6, and B12, reduce the amount of the amino acid homocysteine in the blood. High levels of this substance have been linked to heart disease.

In a new analysis they excluded patients with low and very high B12 levels at baseline. These were likely to have B12 malabsorption or to be taking B12 supplements outside the study.

In the remaining 2155 patients, high-dose vitamin supplements reduced recurrent stroke, death and heart disease by 21 per cent compared with those taking low-dose vitamins, they report in the 1 November issue of Stroke (vol 36, p2404).

The authors suggest that given the fortification of flour with folate, the response to vitamin therapy for lowering homocysteine largely depends on B12 levels of heart patients.

Higher doses of B12 could be required to reduce homocysteine, and thus to reduce stroke and heart attack.

1 comment:

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