The new report is based on a study of more than 32,000 women aged 30 to 55.
Every two to four years, the women completed questionnaires on their medical history, lifestyle, and diet. They provided blood samples at the start of the study.
From 1989-2000, the group had 194 colorectal cancer cases and 410 precancerous cases. The women with those conditions were compared with healthy women of similar backgrounds.
The risk of colorectal cancer was 44% lower for the women with the highest blood level of vitamin B-6 compared with women with the lowest level of vitamin B-6.
Women who had the most vitamin B-6 from foods or supplements were 49% less likely to develop colon cancer.
Journal of the National Cancer Institute, May 4, 2005
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