Tuesday, June 11, 2013

Is Alopecia a barometer for more significant disease?

According to a new study in JAMA Dermatology, patients with Alopecia Areata exhibit an increase in comorbid conditions that include autoimmune diagnoses (thyroid disease in 14.6%, diabetes mellitus in 11.1%, inflammatory bowel disease in 6.3%, systemic lupus erythematosus in 4.3%, rheumatoid arthritis in 3.9%, and psoriasis and psoriatic arthritis in 2.0%), atopy (allergic rhinitis, asthma, and/or eczema in 38.2% and contact dermatitis and other eczema in 35.9%), and mental health problems (depression or anxiety in 25.5%). 

Researchers also found high prevalences of hyperlipidemia (24.5%), hypertension (21.9%), and gastroesophageal reflux disease (17.3%). This profile was different from that seen in a comparison psoriasis and psoriatic arthritis group.

Alopecia areata occurs in people who are apparently healthy and have no skin disorder. Initial presentation most commonly occurs in the late teenage years, early childhood, or young adulthood, but can happen with people of all ages. Patients also tend to have a slightly higher incidence of conditions related to the immune system: asthma, allergies, atopic dermal ailments, and hypothyroidism. 

Physicians caring for patients with Alopecia Areata should consider screening for comorbid conditions such as the aforementioned as well.

1 comment:

cogniterra said...

Add one more...alopecia has been seen in some people who are hypersensitive to electromagnetic fields. For instance, a colleague and her husband developed it when a bank of cell antennas went up on a low building next door. Their knowledge of electrical engineering led them to use special silver dipped fabric for curtains in their window, significantly reducing their exposure, and allowing both their hair (and their concurrently impaired hearing) to come back. (They moved soon thereafter.)
EMF hypersensitivity is positively correlated with the existence of other kinds of sensitivities--allergies, chemical sensitivities, immune disorders, etc.