Glucosamine/Chondoitin versus Cox-2 inhbitors

A randomized, double-blind, study in Annals of Rheumatic Disease found that patients randomized to receive either 400 mg chondroitin sulfate (CS) plus 500 mg glucosamine hydrochloride (GH) 3 times per day or 200 mg COX-2 selective inhibitor celecoxib (Celebrex) once a day for 6 months reported the same osteoarthritis index pain score (50% reduction). Of course, glucosamine and chondoitin is a much safe choice!