Thursday, December 07, 2006

Omega-3, fibre, vitamin E linked to lower Lymphoma risk

The researchers behind the new study, led by Ellen Chang from the Northern California Cancer Center, looked at the dietary intakes of 591 people with non-Hodgkin lymphomas (NHL) and certain lymphoma subtypes, and 460 healthy controls recruited from seven Swedish counties.

“Overall, we found that eating fish and marine fats was associated with lower risk of overall non-Hodgkin lymphomas and certain lymphoma subtypes (which should be examined separately, since NHLs represent a group of several different lymphomas),” Dr. Chang told NutraIngredients.com.

“We also found that consuming certain antioxidant vitamins, commonly found in some fruits and vegetables, was associated with lower risk of overall NHL and some common subtypes.”

After adjusting the results to eliminate potential confounding factors like gender and BMI, Chang and her colleagues report that, while dietary intake of most macronutrients was not associated with NHL risk, average consumption of about 0.8 grams per day of omega-3 or marine fatty acids was associated with a 20 and 60 per cent reduced risk of NHL and its subtypes, compared to those who consumed about 0.2 grams per day.

This also extended to fish oil supplements, with people who supplemented their diet with fish oil at a significantly reduced risk of NHL and its subtypes than people who did not take the supplements (risk reduction of between 30 and 50 per cent).

Strong associations between dietary fibre intake and NHL risk reductions were also observed, said the researchers in the American Journal of Epidemiology. Indeed, Daily average intake of 14.4 grams per 1,000 kcal was linked to a 50 to 60 per cent risk reduction of NHL and all its subtypes.

Dietary consumption of the micronutrients beta-carotene or alpha-tocopherol was also associated with lower NHL risk, said the researchers, with the highest dietary beta-carotene intake (average 4.4 micrograms per day) associated with 40 per cent reduction in NHL risk, compared to the lowest intake (average 1.2 micrograms per day).

Similarly, the highest dietary alpha-tocopherol intake (average 9.8 milligrams per day) associated with 60 per cent reduction in NHL risk, compared to the lowest intake (average 5.0 milligrams per day).

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